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The American Journal of Psychiatry, VOL. 134, No. 3

REGULAR ARTICLES | March 01, 1977

Weight reduction in schizophrenics by molindone

Am J Psychiatry 1977;134:302-304.

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Abstract

The weight-reducing property of molindone, a recently introduced antipsychotic drug, was tested in 9 hospitalized chronic schizophrenic patients. There was an average weight loss of 7.6 kg after 3 months on molindone; most of the loss occurred during the first month. The mechanism producing this weight loss is uncertain, but a central anorexigenic effect may be an important factor.

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