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The American Journal of Psychiatry, VOL. 134, No. 12

Brief Reports | December 01, 1977

The treatment of perceptual disturbances in schizophrenia with naloxone hydrochloride

Am J Psychiatry 1977;134:1408-1410.

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Abstract

The authors treated 12 schizophrenic patients who had overt hallucinatory symptoms with intravenously administered naloxone hydrochloride, a narcotic antagonist purported to have antihallucinatory properties. They found no evidence of the effectiveness of naloxone in preventing hallucinations over that of placebo when administered in a randomized, double-blind fashion.

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