In a double-blind study using each subject as his own control, 6 normal
subjects smoked 20 mg of THC within 10- and 45-minute periods ("fast" and
"slow" conditions, respectively). Each subject also received placebo and
doses of alcohol calculated to be as intoxicating as the THC doses. In fast
conditions, THC induced greater difficulties with tracking information over
time, greater disruptions of self-other interpersonal perceptions, and more
persecutory ideation that did alcohol or placebo. Similar but less marked
differences were found in the slow conditions. As hypothesized, changes in
tracking difficulties, self-other metaperspectives, and persecutory
ideation were substantially and significantly correlated.Abstract Teaser