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The American Journal of Psychiatry, VOL. 132, No. 8

REGULAR ARTICLES | August 01, 1975

Amitriptyline-perphenazine overdose producing delayed hypomania in manic-depressive illness

Am J Psychiatry 1975;132:870-871.

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Abstract

The authors describe a 26-year-old woman who became hypomanic after awakening from a semicomatose state induced by an overdose of amitriptyline-perphenazine (Triavil). She had been depressed and had a strong family history of manic-depressive illness. The case is reported to support previous evidence that dopamine is a mediator for mania.

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