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The American Journal of Psychiatry, VOL. 132, No. 4

REGULAR ARTICLES | April 01, 1975

Platelet monoamine oxidase activity in acute schizophrenia

Am J Psychiatry 1975;132:438-441.

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Abstract

The authors found normal monoamine oxidase (MAO) activity in 40 acute schizophrenic patients, in contrast to previous reports of a genetically linked platelet MAO deficit in chronic schizophrenia. Variations in MAO activity were not significantly associated with the 65 clinical variables analyzed, although there was a tendency for patients in the low-MAO group to have more severely impaired reality testing, more paranoid and grandiose delusions, better prognostic scores, and less restlessness.

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