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The American Journal of Psychiatry, VOL. 131, No. 7

Articles | July 01, 1974

Does Lithium Block the Effects of Amphetamine? A Report of Three Cases

ABRAHAM FLEMENBAUM

Am J Psychiatry 1974;131:820-821.

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Research Psychiatrist and Associate Professor, Department of Psychiatry, Texas Tech University School of Medicine, Lubbock, Tex. 79409

1974, The American Psychiatric Association

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Abstract

The author presents three case reports supporting the hypothesis that lithium therapy inhibits the effect of amphetamine. He suggests that the pharmacologic mechanisms of action of lithium and amphetamine are directly opposite and that lithium could be prophylactic for cases of amphetamine abuse; he suggests further research to evaluate this hypothesis.

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