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The American Journal of Psychiatry, VOL. 130, No. 5

Articles | May 01, 1973

Piperacetazine and Chlorpromazine: A Comparison

ALONZA C. JOHNSON; A. S. KULKARNI

Am J Psychiatry 1973;130:603-605.

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Consultant Psychiatrist, Contra Costa County Hospital, Martinez, Calif. 94553

Clinical Monitor and Research Pharmacologist, Human Health Medical Department, Dow Pharmaceuticals Research Center, Zionsville, Ind. 46077

1973, The American Psychiatric Association

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Abstract

Twenty-six agitated acute schizophrenic patients in a state hospital received intramuscular injections of either piperacetazine or chlorpromazine. Three rating scales were used to assess the effects of the drugs. Both drugs were found to be effective in producing significant improvement in the patients. Piperacetazine appeared to be more potent than chlorpromazine. No side effects were observed.

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