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The American Journal of Psychiatry, VOL. 130, No. 2

Articles | February 01, 1973

Imipramine Therapy and Seizures: Three Children Treated for Hyperactive Behavior Disorders

DAVID BROWN; BERTRAND G. WINSBERG; IRV BIALER; MARK PRESS

Am J Psychiatry 1973;130:210-212.

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An intern at Long Island Jewish Hospital, New Hyde Park, N.Y.

Clinical Assistant Professor, Division of Child Psychiatry, Downstate Medical Center, Brooklyn, N.Y. and Research Medical Director, Child Psychiatric Evaluation Research Unit, New York State Department of Mental Hygiene, 524 Clarkson Ave., Brooklyn, N.Y. 11203

Clinical Associate Professor, Division of Child Psychiatry, Downstate Medical Center, Brooklyn, N.Y. and Principal Research Scientist, Child Psychiatric Evaluation Research Unit, New York State Department of Mental Hygiene, 524 Clarkson Ave., Brooklyn, N.Y. 11203

Clinical Instructor, Division of Child Psychiatry, Downstate Medical Center, Brooklyn, N.Y.

1973, The American Psychiatric Association

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Abstract

The authors report three cases of children who developed seizures while receiving imipramine treatment for hyperactive-aggressive behavior disorders; all three children had organic brain disease but no previous history of seizures. Two of the children remained seizure-free after anticonvulsant medication was added to the imipramine regimen. The authors suggest that clinicians prescribing imipramine be alert to the possible complication of seizures.

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