Advanced Search

The American Journal of Psychiatry, VOL. 128, No. 11

Articles | May 01, 1972

Safety of High-Dose Tricyclic Antidepressant Therapy

MARC A. SCHUCKIT; JOHN P. FEIGHNER

Am J Psychiatry 1972;128:1456-1459.

View Article Information

Chief Resident, Department of Psychiatry, University of California at San Diego School of Medicine, La Jolla, Calif. 92037

Assistant Clinical Professor, Department of Psychiatry, University of California at San Diego School of Medicine, La Jolla, Calif. 92037

1972, American Psychiatric Association

Article

text A A A

PDF of the full text article.

Abstract

The authors report on a series of depressed inpatients and outpatients who received greater-than-recommended doses of the tricyclic antidepressants for 1,505 patient days. These patients tolerated the drugs with a minimum of side effects and, when tested, showed no evidence of hematologic, hepatic, or ocular damage. The authors give some possible explanations for the individual variations in tolerance and response to this high-dose regimen.

Figures in this Article

Your Session has timed out. Please sign back in to continue.

Username

Password

Sign in via Athens (What is this?)

Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.

Forgot Password?

Not a subscriber?

Subscribe Now/Learn More

Purchase Online access to this article for 24 hours

PsychiatryOnline subscription options offer access to the DSM-IV-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.

Submit a Comments

Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of JBJS editorial staff.

* = Required Field

Comment Author(s)*(if multiple authors, separate names by comma)

Example: John Doe

Affiliation & Institution*

Comment Title*

Comment*

Cancel

Topics

Product Recommendation

CME Activity