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The American Journal of Psychiatry, VOL. 127, No. 6

Articles | December 01, 1970

Effect of Lithium Carbonate, Placebo, and Thioridazine on Hyperactive Children

PAUL L. WHITEHEAD; LINCOLN D. CLARK

Am J Psychiatry 1970;127:824-825.

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Instructor in psychiatry, department of psychiatry, University of Utah Medical Center, Salt Lake City, Utah and director, Children's Psychiatric Center of Primary Children's Hospital, Salt Lake City, Utah

Professor of psychiatry, department of psychiatry, University of Utah Medical Center, Salt Lake City, Utah

1971, American Psychiatric Association

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Abstract

The authors describe a pilot study of hyperactive children given lithium carbonate alternately with placebo and thioridazine. There was no difference between the activity level and behavior occurring with lithium intake and that occurring with placebo intake; thioridazine produced some reduction of activity. Six of seven children were described as improved in activity and general behavior, which is attributed to the placebo effect of the treatment.

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