The history of the tranquilizer meprobamate illustrates how factors other than scientific evidence may determine physicians' patterns of drug use. Forceful advertising and publicity, an attitude of general optimism, and uncontrolled studies with favorable results combined to elevate meprobamate to the position of America's magical cure-all tranquilizer. This drug remains in wide use despite a large body of sound scientific data that questions its efficacy. Today easy pharmacologic solutions to the stresses and tensions of life are often sought in place of more effective forms of mastery. This trend, which may not be a healthy one, is fostered by physicians who prescribe tranquilizers indiscriminantly.Abstract Teaser