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The American Journal of Psychiatry, VOL. 126, No. 3

Articles | September 01, 1969

Schizophrenic-Like Reactions and Affective Psychoses Associated with Temporal Lobe Epilepsy: Etiological Factors

P. FLOR-HENRY

Am J Psychiatry 1969;126:400-404.

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Director, Simon Fraser Mental Health Centre, 628 Carnarvon St., New Westminster, B. C., Canada

1970, American Psychiatric Association

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Abstract

A controlled comparative investigation showed that temporal lobe epilepsy of the dominant hemisphere predisposes to psychotic manifestations; epilepsy of the non-dominant temporal lobe is associated with manic-depressive psychotic reactions and epilepsy of the dominant temporal lobe with schizophrenic-like psychotic reactions. Also, the presence of psychomotor seizures and frequent temporal seizures is inversely correlated with psychosis; and in epileptic psychoses, periodicity is correlated with minimal brain damage and chronicity with maximal brain damage.

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