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The American Journal of Psychiatry, VOL. 126, No. 2

Articles | August 01, 1969

Diphenylhydantoin in Neurotic Anxiety

WARREN G. CASE; KARL RICKELS; STANFORD BAZILIAN

Am J Psychiatry 1969;126:254-255.

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Research psychiatrist, Philadelphia General Hospital, 34th St. and Civic Center Blvd., Philadelphia, Pa. 19104

Director of the psychopharmacology unit, Philadelphia General Hospital, 34th St. and Civic Center Blvd., Philadelphia, Pa. 19104

Administrator for psychiatry, Philadelphia General Hospital, 34th St. and Civic Center Blvd., Philadelphia, Pa. 19104

1970, American Psychiatric Association

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Abstract

Anxious-neurotic psychiatric clinic outpatients in social classes IV and V were treated over a four-week period with diphenylhydantoin, 100 mg., twice daily. While some improvement was observed in this patient group, no significant difference was noted between the diphenylhydantoin and a comparable placebo group.

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