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The American Journal of Psychiatry, VOL. 126, No. 9

Articles | March 01, 1970

Nicotinic Acid Side Effects and Toxicity: A Review

LOREN R. MOSHER

Am J Psychiatry 1970;126:1290-1296.

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Chief, center for studies of schizophrenia, clinical research branch, division of extramural research programs, National Institute of Mental Health, 5454 Wisconsin Ave., Chevy Chase, Md. 20015

1970, American Psychiatric Association

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Abstract

The author reviews the literature on the possible toxicity of nicotinic acid, whose therapeutic value in the treatment of schizophrenia is still in dispute. While the drug appears to be relatively harmless, caution in prescribing it is advised, especially for women of childbearing age and for patients with a history of ulcer, gout, diabetes, or liver disease.

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