A four-year survey of the use of thioridazine is reported. A high success rate was obtained in a variety of mental disorders encountered in 1,225 psychiatric patients, both hospitalized and outpatient.The results obtained in the largest group, the schizophrenics, were especially striking. The capacity of thioridazine to suppress the symptoms of schizophrenia was reflected in the prototype of a calm, obedient, well-behaved, and manageable patient.In mental defectives, with and without epilepsy, thioridazine proved to be effective in behavioral problems. Freedom from excessive sedation or obtunding effect made it especially valuable in remotivating outpatients and facilitating their adaptation to the outside world.Results obtained with thioridazine show it to be highly effective, well tolerated, and consistent in its therapeutic action.Abstract Teaser