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The American Journal of Psychiatry, VOL. 123, No. 6

Articles | December 01, 1966

Some Neurophysiologic Differences Between Schizophrenia and Depression

GEORGE B. WHATMORE

Am J Psychiatry 1966;123:712-716.

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Medical-Dental Building, Seattle, Wash. 98101

1966-67, American Psychiatric Association

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Abstract

Fatigue of neurons after a prolonged hyperponesis (measurable electromyographically) may be one factor in the production of depressive states. On the other hand, in acute schizophrenic episodes a disorganization of activity in neuronal networks may take place before fatigue of neurons has time to develop—occurring shortly after the onset of hyperponesis.

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