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A Clinical Technique Using Hg197 for Determining the Blood-Cerebrospinal Fluid Barrier: A Preliminary Report
JAMES JANECEK; GLEN CRAMER; MERLE K. LOKEN; CARL D. KOUTSKY
Am J Psychiatry 1967;123:1005-1007.
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Director of the In-Patient Psychiatric Service, St. Paul-Ramsey Hospital, St. Paul, Minn. 55101
Medical Fellow, Department of Radiology, University of Minnesota Medical School
Associate Professor, Department of Radiology, and Director of the Nuclear Medicine Clinic, University of Minnesota Medical School
Associate Professor, Department of Psychiatry, University of Minnesota Medical School
1966-67, American Psychiatric Association
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Abstract
Five psychiatric patients were given one millicurie of Hg197 intravenously; following this, lumbar and venous punctures were performed. The data suggest that Hg197 passes the blood-cerebrospinal fluid barrier. As indicated by this study and by the literature on the blood-cerebrospinal fluid barrier, radioisotope techniques may prove to be a valuable investigative method.Abstract Teaser
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