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The American Journal of Psychiatry, VOL. 122, No. 3

Articles | September 01, 1965

ESTROGEN TREATMENT OF PATIENTS WITH CHRONIC BRAIN SYNDROME ASSOCIATED WITH CEREBRAL ATHEROSCLEROSIS

KENNETH LIFSHITZ; NATHAN S. KLINE

Am J Psychiatry 1965;122:329-331.

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Research Facility, Rockland State Hospital, Orangeburg, N. Y.

1966 by The American Psychiatric Association

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Abstract

For this severely impaired population of 37 patients suffering from chronic brain syndrome associated with cerebral atherosclerosis, treatment with 1.25 mg./day of conjugated equine estrogens over a period of about one year resulted in no measurable effect on psychological functioning or on mortality as compared to placebo treatment.

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