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The American Journal of Psychiatry, VOL. 120, No. 6

CLINICAL NOTES | December 01, 1963

PROLONGED PERPHENAZINE THERAPY AND THYROID FUNCTION

FRANK J. AYD

Am J Psychiatry 1963;120:592-594.

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Abstract

The findings in this survey do not support those reported by Cranswick, et al. The slight deviations from normal values in 3 of 25 patients (1 below normal and 2 above) are clinically and statistically insignificant. On the basis of the PBI determinations in these 25 patients on longterm perphenazine therapy, it may be concluded that this phenothiazine has no direct or indirect pathological influence on the thyroid gland.

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