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The American Journal of Psychiatry, VOL. 118, No. 6

CLINICAL NOTES | December 01, 1961

TETRABENACINE TREATMENT IN PERSISTING DYSKINESIA CAUSED BY PSYCHOPHARMACA

ERIK BRANDRUP

Am J Psychiatry 1961;118:551-552.

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Sct. Hans Mental Hospital, Roskilde, Denmark.

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Abstract

In 3 patients suffering from schizophrenia and one patient with arteriosclerotic dementia persisting dyskinetic movements caused by psychopharmaca disappeared almost or completely after treatment with tetrabenacine (Nitoman®). The schizophrenics received a daily dose of 75 mg., whereas it was necessary to give the patient with dementia 150-300 mg. per day in order to obtain a satisfactory effect. This patient responded by developing a certain degree of drowsiness, while no side effects were observed in the other cases.

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