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The American Journal of Psychiatry, VOL. 113, No. 11

Article | May 01, 1957

CHLORPROMAZINE IN THE TREATMENT OF MENTAL ILLNESS. IV: FINAL RESULTS WITH ANALYSIS OF DATA ON 1,523 PATIENTS

HERMAN C. B. DENBER; ETTA G. BIRD

Am J Psychiatry 1957;113:972-978.

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Director of psychiatric research, Manhattan State Hospital, Ward's Island, New York, N. Y., and instructor in psychiatry, College of Physicians and Surgeons, Columbia University, New York, N. Y.

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Abstract

1. Of 1, 523 patients treated with chlorpromazine from 1-15 months, 81.8% showed improvement.2. Problems concerning dose, side-effects, and clinical results have been considered.3. Female patients used higher doses, had a proportionately larger number of sideeffects, and showed a better discharge rate than males.4. Some theoretical considerations of these findings have been reviewed.

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