Paroxysmal disorders of the nervous system such as epilepsy, migraine, and Meniere's disease can develop a disturbance of electrolyte and water balance of cerebral and labyrinthine tissues when the paroxysms of the attack become frequent and severe. Experimental work and tissue analysis support this assumption. The introduction of ion exchange resins into the field of therapy has offered an opportunity to influence electrolyte (particularly Na and K) and water balance in these conditions. Clinical experience and results from the use of these resins have established their usefulness in the therapy of epilepsy, migraine, and Meniere's disease.Abstract Teaser