1. The orbital cortex was partly isolated on 22 schizophrenics, and good response was observed where there were symptoms of introversion, blockage, emotional dulling and depersonalisation present.2. The isolation of the orbital lobe produced a triad of symptoms described as: extroversion, increased motor activity and euphoria.3. It was emphasised that the new symptoms produced, balance well with the pre-existing psychotic symptoms.Abstract Teaser