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Cover: This issue of the Journal, which focuses on brain alterations across various disorders with an emphasis on cortical and limbic regions, begins with an overview by Rothem Kovner et al. (p. 987) that lays the groundwork for understanding the neuroanatomical and functional components of the limbic system and its prefrontal connectivity. Images are schematics depicting prefrontal cortex–hippocampal connectivity (left) and prefrontal cortex–amygdala connectivity (right). Images courtesy of Rothem Kovner.
