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American Journal of Psychiatry

Volume 171, Issue 9

September 2014

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In This Issue

September 2014

Page:A11
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.1719issue

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Editorials

September 2014

Aggression in Schizophrenia and its Relationship to Neural Circuitry of Urgency

Philip R. Szeszko, Ph.D.

Pages:897–900
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050629

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September 2014

Priming the Brain for Psychosis: Maternal Inflammation During Fetal Development and the Risk of Later Psychiatric Disorder

Mary Cannon, M.D., Ph.D.,
Mary C. Clarke, Ph.D., and
David R. Cotter, M.D., Ph.D.

Pages:901–905
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14060749

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September 2014

Identifying Pathways Leading to Prefrontal GABA-ergic Interneuron Dysfunction in Schizophrenia

Vikaas S. Sohal, M.D., Ph.D.

Pages:906–909
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14060750

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September 2014

Symptom Outcome in Early-Onset Bipolar Disorder: Could Be Better, Could Be Worse

Gabrielle A. Carlson, M.D.

Pages:910–912
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050677

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Commentary

September 2014

Psychiatry and Efforts to Build Community in Iraq

Amir A. Afkhami, M.D., Ph.D.

Pages:913–915
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14070815

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Introspection

September 2014

Purple and Turquoise Ribbons

Jennifer Bremer, M.D.

Pages:916–917
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14060777

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Treatment in Psychiatry

September 2014

Disruptive Mood Dysregulation Disorder: A New Diagnostic Approach to Chronic Irritability in Youth

Amy Krain Roy, Ph.D.,
Vasco Lopes, Psy.D., and
Rachel G. Klein, Ph.D.

Pages:918–924
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13101301

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Disruptive mood dysregulation disorder (DMDD), a newcomer to psychiatric nosology, addresses the need for improved classification and treatment of children exhibiting chronic nonepisodic irritability and severe temper outbursts. In recent years, many of ...

Perspectives in Global Mental Health

September 2014

Major Depression in Postconflict Northern Uganda: A Case Report

Etheldreda Nakimuli-Mpungu, M.Med.(Psych), Ph.D.,
Raymond Odokonyero, M.Med.(Psych),
Jean Laker, B.S.W., and
Stephen Alderman, M.D.

Pages:925–928
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14020261

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Images in Psychiatry

September 2014

Wandering or Unhappy Mind?

Ladislav Kesner, Ph.D.

Pages:929–930
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2013.13121629

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Reviews and Overviews

September 2014

The Structure of Psychiatric Science

Kenneth S. Kendler, M.D.

Pages:931–938
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13111539

Abstract
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This essay explores the etiology of psychiatric disorders across biological, psychological, and environmental risk factors, and outlines three central paradigms for risk analysis, mechanisms of illness, and first-person approaches to patient empathy.

Articles

September 2014

Cortical Thinning, Functional Connectivity, and Mood-Related Impulsivity in Schizophrenia: Relationship to Aggressive Attitudes and Behavior

Matthew J. Hoptman, Ph.D.,
Daniel Antonius, Ph.D.,
Cristina J. Mauro, Ph.D.,
Emily M. Parker, B.A., and
Daniel C. Javitt, M.D., Ph.D.

Pages:939–948
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13111553

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A robust association was found in patients with schizophrenia between cortical thinning in ventral prefrontal regions and increased impulsivity, which likely reflects an impaired interaction with regions affecting cognitive control regions. As urgency ...

September 2014

Reading Deficits in Schizophrenia and Individuals at High Clinical Risk: Relationship to Sensory Function, Course of Illness, and Psychosocial Outcome

Nadine Revheim, Ph.D.,
Cheryl M. Corcoran, M.D.,
Elisa Dias, Ph.D.,
Esther Hellmann, M.Phil.,
Antigona Martinez, Ph.D.,
Pamela D. Butler, Ph.D.,
Jonathan M. Lehrfeld, M.A.,
Joanna DiCostanzo, M.P.H.,
Jennifer Albert, B.A., and
Daniel C. Javitt, M.D., Ph.D.

Pages:949–959
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13091196

Abstract
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ObjectiveThe ability to read passages of information fluently and with comprehension is a basic component of socioeconomic success. Reading ability depends on the integrity of underlying visual and auditory (phonological) systems. This study investigated ...

September 2014

Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort

Sarah Canetta, Ph.D.,
Andre Sourander, M.D.,
Heljä-Marja Surcel, Ph.D.,
Susanna Hinkka-Yli-Salomäki, Ph.Lic.,
Jaana Leiviskä, Ph.D.,
Christoph Kellendonk, Ph.D.,
Ian W. McKeague, Ph.D., and
Alan S. Brown, M.D., M.P.H.

Pages:960–968
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13121579

Abstract
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Maternal inflammation level during pregnancy was related to risk of schizophrenia in offspring, adding new evidence for the association of infection and immune activation with the development of the disorder.

September 2014

Lower Expression of Glutamic Acid Decarboxylase 67 in the Prefrontal Cortex in Schizophrenia: Contribution of Altered Regulation by Zif268

Sohei Kimoto, M.D., Ph.D.,
H. Holly Bazmi, M.S., and
David A. Lewis, M.D.

Pages:969–978
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14010004

Abstract
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ObjectiveCognitive deficits of schizophrenia may be due at least in part to lower expression of the 67-kDa isoform of glutamic acid decarboxylase (GAD67), a key enzyme for GABA synthesis, in the dorsolateral prefrontal cortex of individuals with ...

September 2014

Effects of Schizophrenia Risk Variation in the NRG1 Gene on NRG1-IV Splicing During Fetal and Early Postnatal Human Neocortical Development

Clare Paterson, Ph.D.,
Yanhong Wang, M.D.,
Joel E. Kleinman, M.D., Ph.D., and
Amanda J. Law, Ph.D.

Pages:979–989
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13111518

Abstract
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Mapping the transcriptional and genetic regulation of NRG1s during normal human brain development could help identify a potential mechanism of early risk for schizophrenia at the NRG1 locus.

September 2014

Longitudinal Trajectories and Associated Baseline Predictors in Youths With Bipolar Spectrum Disorders

Boris Birmaher, M.D.,
Mary Kay Gill, M.S.N.,
David A. Axelson, M.D.,
Benjamin I. Goldstein, M.D., Ph.D.,
Tina R. Goldstein, Ph.D.,
Haifeng Yu, M.S.,
Fangzi Liao, M.S.,
Satish Iyengar, Ph.D.,
Rasim S. Diler, M.D.,
Michael Strober, Ph.D.,
Heather Hower, M.S.W.,
Shirley Yen, Ph.D.,
Jeffrey Hunt, M.D.,
John A. Merranko, M.A.,
Neal D. Ryan, M.D., and
Martin B. Keller, M.D.

Pages:990–999
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.13121577

Abstract
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ObjectiveThe authors sought to identify and evaluate longitudinal mood trajectories and associated baseline predictors in youths with bipolar disorder.MethodA total of 367 outpatient youths (mean age, 12.6 years) with bipolar disorder with at least 4 ...

Letters to the Editor

September 2014

Consider ECT for Treatment-Resistant Childhood Schizophrenia

Matthew Majeske, M.D., and
Charles H. Kellner, M.D.

Page:1000
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050628

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September 2014

Response to Majeske and Kellner

David I. Driver, M.D.,
Judith L. Rapoport, M.D., and
Nitin Gogtay, M.D.

Page:1000
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050628r

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September 2014

Right Versus Left Hippocampal Activity as a Biomarker in Schizophrenia

Jeffrey A. Mattes, M.D.

Pages:1000–1001
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050687

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Correction

September 2014

Page:1001
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.1719correction

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Letters to the Editor

September 2014

Response to Mattes

Jason R. Tregellas, Ph.D.

Page:1001
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050687r

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Book Forum

September 2014

Handbook of Good Psychiatric Management for Borderline Personality Disorder

John M. Oldham, M.D.

Pages:1002–1003
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14040467

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September 2014

Normal Child and Adolescent Development: A Psychodynamic Primer

Celeste St. John-Larkin, M.D.

Pages:1003–1004
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14050623

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September 2014

Managing the Side Effects of Psychotropic Medications

Jeffrey Katzman, M.D.

Pages:1004–1005
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14040427

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September 2014

Eating Drugs: Psychopharmaceutical Pluralism in India

Vihang N. Vahia, M.D.

Pages:1005–1006
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.14040541

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Books Received

September 2014

Page:1006
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.1719books

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Official Actions

September 2014

Reports to the Membership

Pages:1007–1014
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.1710901

First Page
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September 2014

2013 Annual Report of the American Board of Psychiatry and Neurology, Inc.

Pages:1015–1018
Published Online:1 September 2014

https://doi.org/10.1176/appi.ajp.2014.1710902

First Page
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