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American Journal of Psychiatry

Volume 171, Issue 2

February 2014

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In This Issue

February 2014

Page:A18
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.17102issue

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Editorials

February 2014

Lurasidone and Bipolar Disorder

R.H. Belmaker, M.D.

Pages:131–133
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091240

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February 2014

Computer Aids for the Diagnosis of Anxiety and Depression

Helena Chmura Kraemer, Ph.D., and
Robert Freedman, M.D.

Pages:134–136
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13111458

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February 2014

Minding the Aging Brain: Are We Ready for Personalized Medicine?

Jason Karlawish, M.D., and
Robert C. Green, M.D., M.P.H.

Pages:137–139
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13111536

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February 2014

Community, Siblings, Heritability and the Risk for Drug Abuse

Christian Hopfer, M.D.

Pages:140–141
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13111508

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Commentary

February 2014

DSM-5 Clinical and Public Health Committee: Challenges and Considerations

Joel Yager, M.D., and
John S. Mcintyre, M.D.

Pages:142–144
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13030347

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Clinical Case Conference

February 2014

Development of Schizoaffective Psychosis in the Course of a Long-Term Occupation as Spiritual Healer: Coincidence or Causality?

Julia Sadzio, M.D.,
Henning Vieker, M.D.,
Oliver Gruber, M.D., and
David Zilles, M.D.

Pages:145–148
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13020174

Abstract
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Psychotic reactions in the context of meditation and esoteric practices have been described in the psychiatric literature. In most cases, these psychotic conditions are transient and do not lead to functional impairment. The authors present the case of a ...

Images in Psychiatry

February 2014

The Old and the New Eastern State Hospital in Lexington, Kentucky

Jose de Leon, M.D.,
Shane Shoemaker, M.L.S., and
Allen Brenzel, M.D., M.B.A.

Pages:149–150
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13070959

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Reviews and Overviews

February 2014

Pharmacological Treatments of Non-Substance-Withdrawal Delirium: A Systematic Review of Prospective Trials

Joseph I. Friedman, M.D.,
Laili Soleimani, M.D.,
Daniel P. McGonigle, M.D.,
Claudine Egol, M.D., and
Jeffrey H. Silverstein, M.D.

Pages:151–159
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13040458

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The pharmacological strategies reviewed here may be more effective at preventing delirium—associated with greater hospital-based complications, including mortality—than at treating delirium once it develops.

Articles

February 2014

Lurasidone Monotherapy in the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

Antony Loebel, M.D.,
Josephine Cucchiaro, Ph.D.,
Robert Silva, Ph.D.,
Hans Kroger, M.P.H., M.S.,
Jay Hsu, Ph.D.,
Kaushik Sarma, M.D., and
Gary Sachs, M.D.

Pages:160–168
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13070984

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In July 2013, the Food and Drug Administration approved lurasidone for the treatment of bipolar I depression. Two studies discussing its monotherapy and adjunctive use that were pivotal in obtaining this approval are featured in this issue.

February 2014

Lurasidone as Adjunctive Therapy With Lithium or Valproate for the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

Antony Loebel, M.D.,
Josephine Cucchiaro, Ph.D.,
Robert Silva, Ph.D.,
Hans Kroger, M.P.H., M.S.,
Kaushik Sarma, M.D.,
Jane Xu, Ph.D., and
Joseph R. Calabrese, M.D.

Pages:169–177
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13070985

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ObjectiveFew studies have been reported that support the efficacy of adjunctive therapy for patients with bipolar I depression who have had an insufficient response to monotherapy with mood-stabilizing agents. The authors investigated the efficacy of ...

February 2014

Do Comorbid Anxiety Disorders Moderate the Effects of Psychotherapy for Bipolar Disorder? Results From STEP-BD

Thilo Deckersbach, Ph.D.,
Amy T. Peters, B.A.,
Louisa Sylvia, Ph.D.,
Anna Urdahl, B.A.,
Pedro V.S. Magalhães, M.D., Ph.D.,
Michael W. Otto, Ph.D.,
Ellen Frank, Ph.D.,
David J. Miklowitz, Ph.D.,
Michael Berk, M.D., Ph.D.,
Gustavo Kinrys, M.D., and
Andrew Nierenberg, M.D.

Pages:178–186
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13020225

Abstract
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Adding intensive psychotherapy to medication for depressed patients with bipolar I or II disorder increases the likelihood of recovery in those who also have a lifetime diagnosis of an anxiety disorder. Adjunctive intensive psychotherapy is especially ...

February 2014

Development of the CAT-ANX: A Computerized Adaptive Test for Anxiety

Robert D. Gibbons, Ph.D.,
David J. Weiss, Ph.D.,
Paul A. Pilkonis, Ph.D.,
Ellen Frank, Ph.D.,
Tara Moore, M.A., M.P.H.,
Jong Bae Kim, Ph.D., and
David J. Kupfer, M.D.

Pages:187–194
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13020178

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ObjectiveThe authors developed a computerized adaptive test for anxiety that decreases patient and clinician burden and increases measurement precision.MethodA total of 1,614 individuals with and without generalized anxiety disorder from a psychiatric ...

February 2014

Effect of Antidepressant Medication Use on Emotional Information Processing in Major Depression

Tony T. Wells, Ph.D.,
Elise M. Clerkin, Ph.D.,
Alissa J. Ellis, Ph.D., and
Christopher G. Beevers, Ph.D.

Pages:195–200
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.12091243

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ObjectiveAcute administration of antidepressant medication increases emotional information processing for positive information in both depressed and healthy persons. This effect is likely relevant to the therapeutic actions of these medications, but it ...

February 2014

Effect of Knowledge of APOE Genotype on Subjective and Objective Memory Performance in Healthy Older Adults

Tara T. Lineweaver, Ph.D.,
Mark W. Bondi, Ph.D.,
Douglas Galasko, M.D., and
David P. Salmon, Ph.D.

Pages:201–208
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.12121590

Abstract
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Older adults who know they have the e4 allele of the apolipoprotein E (APOE) gene, a risk factor for Alzheimer’s disease, perform worse on objective tests of verbal memory than do those who do not know they have the allele. Also discovered was that ...

February 2014

Genetic and Family and Community Environmental Effects on Drug Abuse in Adolescence: A Swedish National Twin and Sibling Study

Kenneth S. Kendler, M.D.,
Hermine H. Maes, Ph.D.,
Kristina Sundquist, M.D., Ph.D.,
Henrik Ohlsson, Ph.D., and
Jan Sundquist, M.D., Ph.D.

Pages:209–217
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.12101300

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ObjectiveUsing Swedish nationwide registry data, the authors investigated genetic and environmental risk factors in the etiology of drug abuse by twin sibling modeling. The authors followed up with epidemiological analyses to identify shared environmental ...

February 2014

A Nationwide Study on the Risk of Autoimmune Diseases in Individuals With a Personal or a Family History of Schizophrenia and Related Psychosis

Michael E. Benros, M.D., Ph.D.,
Marianne G. Pedersen, M.Sc.,
Helle Rasmussen, M.Sc.,
William W. Eaton, Ph.D.,
Merete Nordentoft, Dr.Med.Sc., and
Preben B. Mortensen, Dr.Med.Sc.

Pages:218–226
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13010086

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ObjectivePrevious research has found an increased risk of schizophrenia in individuals with autoimmune diseases and smaller but significant associations with a family history of autoimmune diseases. This study investigates, for the first time, the ...

Letters to the Editor

February 2014

Challenges in Estimating Mortality Risk From Antipsychotics in People With Alzheimer’s Disease

Ryan M. Carnahan, Pharm.D., M.S.

Page:227
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091231

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February 2014

Response to Carnahan

Oscar L. Lopez, M.D., and
James T. Becker, Ph.D.

Pages:227–228
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091231r

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February 2014

Assisted Outpatient Treatment Services and the Influence of Compulsory Treatment

Tom Burns, F.R.C.Psych.

Page:228
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091223

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February 2014

Response to Burns

Jeffrey W. Swanson, Ph.D., and
Marvin Swartz, M.D.

Pages:228–229
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091223r

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February 2014

Type 1 Diabetes Mellitus and Mortality Risk in Patients with Anorexia Nervosa

Kim Masters, M.D.

Page:229
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13081149

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Book Forum

February 2014

Triumphs of Experience: The Men of the Harvard Grant Study

Dilip V. Jeste, M.D., and
Maja Gawronska, M.A.

Pages:230–231
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13111502

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February 2014

A Disability of the Soul: An Ethnography of Schizophrenia and Mental Illness in Contemporary Japan

Kenji Hashimoto, Ph.D.

Page:231
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091206

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February 2014

Mind, Modernity, Madness: The Impact of Culture on Human Experience

Joseph Westermeyer, M.D., M.P.H., Ph.D.

Pages:231–232
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13091242

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February 2014

Autism and Other Neurodevelopmental Disorders

Cassie Karlsson, M.D.

Pages:232–233
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.13030349

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Books Received

February 2014

Page:234
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2014.17102books

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Official Actions

February 2014

APA Council Reports

Pages:235–244
Published Online:1 February 2014

https://doi.org/10.1176/appi.ajp.2013.1710201

First Page
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