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American Journal of Psychiatry

Volume 170, Issue 8

August 2013

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In This Issue

August 2013

Page:A16
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.1708issue

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Editorials

August 2013

The Unrecognized Side of Bipolar Disorder

Robert M.A. Hirschfeld, M.D.

Pages:815–817
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13050656

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August 2013

Searching for More Effective Smoking Cessation Treatment

Robert Freedman, M.D.

Pages:818–820
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13060758

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August 2013

Schizophrenia as a Human Leukocyte Antigen-Associated Disease Revisited

Peter McGuffin, Ph.D., F.R.C.P., and
Robert A. Power, M.Sc.

Pages:821–823
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13030336

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August 2013

Eating Disorders and Risk of Death

Scott Crow, M.D.

Pages:824–825
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13050654

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Introspection

August 2013

Anita Aijaz, M.B.B.S.

Pages:826–827
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040449

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Treatment in Psychiatry

August 2013

An Adolescent With Nonsuicidal Self-Injury: A Case and Discussion of Neurobiological Research on Emotion Regulation

Kathryn R. Cullen, M.D.,
Melinda K. Westlund, B.A.,
Lori L. LaRiviere, M.D., and
Bonnie Klimes-Dougan, Ph.D.

Pages:828–831
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12121598

Abstract
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The management of nonsuicidal self-injurious behavior is a common focus of clinical care, particularly in the treatment of adolescents and young adults. Increased recognition of this problem has led to proposed criteria for future study in DSM-5, which ...

Images in Psychiatry

August 2013

Artemisia Gentileschi, 1593–1653

Peter J. Buckley, M.D.

Pages:832–833
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2012.12101313

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Reviews and Overviews

August 2013

DSM-5 Criteria for Substance Use Disorders: Recommendations and Rationale

Deborah S. Hasin, Ph.D.,
Charles P. O’Brien, M.D., Ph.D.,
Marc Auriacombe, M.D.,
Guilherme Borges, Sc.D.,
Kathleen Bucholz, Ph.D.,
Alan Budney, Ph.D.,
Wilson M. Compton, M.D., M.P.E.,
Thomas Crowley, M.D.,
Walter Ling, M.D.,
Nancy M. Petry, Ph.D.,
Marc Schuckit, M.D., and
Bridget F. Grant, Ph.D.

Pages:834–851
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12060782

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Since DSM-IV was published in 1994, its approach to substance use disorders has come under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but concerns have also arisen. The DSM-5 Substance-Related Disorders Work ...

Articles

August 2013

Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study

Carla Torrent, Ph.D.,
Caterina del Mar Bonnin, Ph.D.,
Anabel Martínez-Arán, Ph.D.,
Jesús Valle, M.D., Ph.D.,
Benedikt L. Amann, M.D., Ph.D.,
Ana González-Pinto, M.D., Ph.D.,
José Manuel Crespo, M.D., Ph.D.,
Ángela Ibáñez, M.D., Ph.D.,
Mari Paz Garcia-Portilla, M.D., Ph.D.,
Rafael Tabarés-Seisdedos, M.D., Ph.D.,
Celso Arango, M.D., Ph.D.,
Francesc Colom, Ph.D.,
Brisa Solé, Psy.D.,
Isabella Pacchiarotti, M.D., Ph.D.,
Adriane R. Rosa, Ph.D.,
Jose Luis Ayuso-Mateos, M.D., Ph.D.,
Celia Anaya, Ph.D.,
Patricia Fernández, Ph.D.,
Ramon Landín-Romero, Ph.D.,
Silvia Alonso-Lana, M.Sc.,
Jordi Ortiz-Gil, Ph.D.,
Bàrbara Segura, Ph.D.,
Sara Barbeito, Ph.D.,
Patricia Vega, Psy.D.,
Miryam Fernández, Ph.D.,
Amaia Ugarte, Ph.D.,
Marta Subirà, M.B.B.S., M.D.,
Ester Cerrillo, M.B.B.S., M.D.,
Núria Custal, M.D., Ph.D.,
José Manuel Menchón, M.D., Ph.D.,
Jerónimo Saiz-Ruiz, M.D., Ph.D.,
Jose Maria Rodao, Ph.D.,
Sandra Isella, Ph.D.,
Analucía Alegría, M.Sc.,
Susana Al-Halabi, Ph.D.,
Julio Bobes, M.D., Ph.D.,
Gonzalo Galván, Ph.D.,
Pilar A. Saiz, M.D., Ph.D.,
Vicent Balanzá-Martínez, M.D., Ph.D.,
Gabriel Selva, M.D., Ph.D.,
Inmaculada Fuentes-Durá, Ph.D.,
Patricia Correa, Psy.D.,
María Mayoral, Ph.D.,
Guadalupe Chiclana, Ph.D.,
Jessica Merchan-Naranjo, M.Sc.,
Marta Rapado-Castro, Ph.D.,
Manel Salamero, M.D., Ph.D., and
Eduard Vieta, M.D., Ph.D.

Pages:852–859
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2012.12070971

Abstract
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This novel neurocognitive intervention significantly improved occupational and interpersonal functioning in patients with bipolar I and II disorder

August 2013

Adapting Smoking Cessation Treatment According to Initial Response to Precessation Nicotine Patch

Jed E. Rose, Ph.D., and
Frédérique M. Behm, C.R.A.

Pages:860–867
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12070919

Abstract
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Smokers who can’t reduce their cigarette intake using precessation nicotine patch treatment can benefit from alternative therapies, such as augmenting the patch with bupropion or switching to varenicline. An adaptive treatment plan can increase smoking ...

August 2013

Association of GSK-3β Genetic Variation With GSK-3β Expression, Prefrontal Cortical Thickness, Prefrontal Physiology, and Schizophrenia

Giuseppe Blasi, M.D., Ph.D.,
Francesco Napolitano, Ph.D.,
Gianluca Ursini, M.D., Ph.D.,
Annabella Di Giorgio, M.D., Ph.D.,
Grazia Caforio, M.D., Ph.D.,
Paolo Taurisano, Ph.D.,
Leonardo Fazio, Ph.D.,
Barbara Gelao, Ph.D.,
Maria Teresa Attrotto, M.D.,
Lucia Colagiorgio, M.D.,
Giovanna Todarello, M.D.,
Francesco Piva, Eng., Ph.D.,
Apostolos Papazacharias, M.D.,
Rita Masellis, Ph.D.,
Marina Mancini, Ph.D.,
Annamaria Porcelli, Ph.D.,
Raffaella Romano, Ph.D.,
Antonio Rampino, M.D., Ph.D.,
Tiziana Quarto, Ph.D.,
Matteo Giulietti, Ph.D.,
Barbara K. Lipska, Ph.D.,
Joel E. Kleinman, M.D., Ph.D.,
Teresa Popolizio, M.D.,
Daniel R. Weinberger, M.D.,
Alessandro Usiello, Ph.D., and
Alessandro Bertolino, M.D., Ph.D.

Pages:868–876
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2012.12070908

Abstract
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ObjectiveGlycogen synthase kinase 3β (GSK-3β) is an enzyme implicated in neurodevelopmental processes with a broad range of substrates mediating several canonical signaling pathways in the brain. The authors investigated the association of variation in ...

August 2013

The Role of the Major Histocompatibility Complex Region in Cognition and Brain Structure: A Schizophrenia GWAS Follow-Up

James T.R. Walters, M.R.C.Psych., Ph.D.,
Dan Rujescu, M.D.,
Barbara Franke, Ph.D.,
Ina Giegling, Ph.D.,
Alejandro Arias Vásquez, Ph.D.,
April Hargreaves, M.Sc.,
Giancarlo Russo, Ph.D.,
Derek W. Morris, Ph.D.,
Martine Hoogman, M.Sc.,
Andrea Da Costa, Ph.D.,
Valentina Moskvina, Ph.D.,
Guillén Fernández, M.D., Ph.D.,
Michael Gill, M.R.C.Psych., Ph.D.,
Aiden Corvin, M.R.C.Psych., Ph.D.,
Michael C. O’Donovan, F.R.C.Psych., Ph.D.,
Gary Donohoe, Ph.D., and
Michael J. Owen, F.R.C.Psych., Ph.D.

Pages:877–885
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12020226

Abstract
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ObjectiveThe authors investigated the effects of recently identified genome-wide significant schizophrenia genetic risk variants on cognition and brain structure.MethodA panel of six single-nucleotide polymorphisms (SNPs) was selected to represent genome-...

August 2013

Diffusion Tensor Imaging White Matter Endophenotypes in Patients With Schizophrenia or Psychotic Bipolar Disorder and Their Relatives

Pawel Skudlarski, Ph.D.,
David J. Schretlen, Ph.D.,
Gunvant K. Thaker, M.D.,
Michael C. Stevens, Ph.D.,
Matcheri S. Keshavan, M.D.,
John A. Sweeney, Ph.D.,
Carol A. Tamminga, M.D.,
Brett A. Clementz, Ph.D.,
Kasey O’Neil, B.Sc., and
Godfrey D. Pearlson, M.D.

Pages:886–898
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12111448

Abstract
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ObjectiveBoth schizophrenia and bipolar disorder are hypothesized to involve disordered brain connectivity. Prior studies show low white matter integrity, measured with diffusion tensor imaging, for both disorders. The authors studied disease specificity ...

August 2013

White Matter Microstructure and Atypical Visual Orienting in 7-Month-Olds at Risk for Autism

Jed T. Elison, Ph.D.,
Sarah J. Paterson, Ph.D.,
Jason J. Wolff, Ph.D.,
J. Steven Reznick, Ph.D.,
Noah J. Sasson, Ph.D.,
Hongbin Gu, Ph.D.,
Kelly N. Botteron, M.D.,
Stephen R. Dager, M.D.,
Annette M. Estes, Ph.D.,
Alan C. Evans, Ph.D.,
Guido Gerig, Ph.D.,
Heather C. Hazlett, Ph.D.,
Robert T. Schultz, Ph.D.,
Martin Styner, Ph.D.,
Lonnie Zwaigenbaum, M.D.,
Joseph Piven, M.D., and
for the IBIS Network

Pages:899–908
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2012.12091150

Abstract
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Specific differences in visual orienting, critical in social-cognitive development, are associated with differences in white matter microstructure of the splenium.

August 2013

High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression

Marian L. Hamshere, Ph.D.,
Kate Langley, Ph.D.,
Joanna Martin, B.Sc.(Hons),
Sharifah Shameem Agha, M.Sc.,
Evangelia Stergiakouli, Ph.D.,
Richard J.L. Anney, Ph.D.,
Jan Buitelaar, M.D.,
Stephen V. Faraone, Ph.D.,
Klaus-Peter Lesch, M.D.,
Benjamin M. Neale, Ph.D.,
Barbara Franke, Ph.D.,
Edmund Sonuga-Barke, Ph.D.,
Philip Asherson, M.R.C.Psych., Ph.D.,
Andrew Merwood, M.Sc.,
Jonna Kuntsi, Ph.D.,
Sarah E. Medland, Ph.D.,
Stephan Ripke, M.D.,
Hans-Christoph Steinhausen, M.D., Ph.D.,
Christine Freitag, M.D., M.A,
Andreas Reif, M.D.,
Tobias J. Renner, M.D.,
Marcel Romanos, M.D.,
Jasmin Romanos, M.D.,
Andreas Warnke, M.D.,
Jobst Meyer, Ph.D.,
Haukur Palmason, Ph.D.,
Alejandro Arias Vasquez, Ph.D.,
Nanda Lambregts-Rommelse, Ph.D.,
Herbert Roeyers, M.D., Ph.D.,
Joseph Biederman, M.D.,
Alysa E. Doyle, Ph.D.,
Hakon Hakonarson, M.D., Ph.D.,
Aribert Rothenberger, M.D.,
Tobias Banaschewski, M.D., Ph.D.,
Robert D. Oades, Ph.D.,
James J. McGough, M.D.,
Lindsey Kent, M.D., Ph.D.,
Nigel Williams, Ph.D.,
Michael J. Owen, F.R.C.Psych., Ph.D.,
Peter Holmans, Ph.D.,
Michael C. O’Donovan, F.R.C.Psych., Ph.D., and
Anita Thapar, F.R.C.Psych., Ph.D.

Pages:909–916
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12081129

Abstract
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ObjectiveAlthough attention deficit hyperactivity disorder (ADHD) is highly heritable, genome-wide association studies (GWAS) have not yet identified any common genetic variants that contribute to risk. There is evidence that aggression or conduct ...

August 2013

A Longitudinal Investigation of Mortality in Anorexia Nervosa and Bulimia Nervosa

Debra L. Franko, Ph.D.,
Aparna Keshaviah, Sc.M.,
Kamryn T. Eddy, Ph.D.,
Meera Krishna, B.A.,
Martha C. Davis, B.A.,
Pamela K. Keel, Ph.D., and
David B. Herzog, M.D.

Pages:917–925
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.12070868

Abstract
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ObjectiveAlthough anorexia nervosa has a high mortality rate, our understanding of the timing and predictors of mortality in eating disorders is limited. The authors investigated mortality in a long-term study of patients with eating disorders.Method...

Letters to the Editor

August 2013

Practice-Based or Telemedicine-Based Collaborative Care for Depression

Henry White, M.D.

Page:926
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040471

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August 2013

Response to White

John C. Fortney, Ph.D.,
Jeffrey M. Pyne, M.D.,
Gregory E. Simon, M.D., M.P.H., and
Evette J. Ludman, Ph.D.

Pages:926–927
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040471r

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August 2013

Bipolar Disorder, Schizophrenia, and Metabolic Syndrome

Francesco Bartoli, M.D., Ph.D.,
Giuseppe Carrà, M.D., M.Sc., Ph.D.,
Cristina Crocamo, M.Sc.,
Daniele Carretta, M.D., and
Massimo Clerici, M.D., Ph.D.

Pages:927–928
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040447

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August 2013

Response to Bartoli et al.

Davy Vancampfort, Ph.D.,
Alex J. Mitchell, M.D.,
Christoph U. Correll, M.D.,
Pascal Sienaert, M.D., Ph.D., and
Marc De Hert, M.D., Ph.D.

Pages:928–929
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040447r

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August 2013

Antepartum Depression: Treatment With Computer-Assisted Cognitive-Behavioral Therapy

Liisa Hantsoo, Ph.D.,
C. Neill epperson, M.D.,
Michael E. Thase, M.D., and
Deborah r. Kim, M.D.

Pages:929–930
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13020254

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August 2013

Clozapine-Induced Obsessive-Compulsive Symptoms in Bipolar Disorder

Nicholas T. Lemke, M.S., and
Juan R. Bustillo, M.D.

Page:930
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13010144

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Book Forum

August 2013

The Placebo Effect in Clinical Practice

Stefan Pallanti, M.D., Ph.D.

Pages:931–932
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040482

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August 2013

The Pathological Family: Postwar America and the Rise of Family Therapy

Alison M. Heru, M.D.

Pages:932–933
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13040505

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August 2013

Care of Children Exposed to the Traumatic Effects of Disaster

Rupinder Legha, M.D., and

Daniel Savin, M.D.

Pages:933–934
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13030318

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August 2013

Elements of Culture and Mental Health: Critical Questions for Clinicians

Rudra Prakash, M.D., D.F.A.P.A.

Page:933
Published Online:1 August 2013

https://doi.org/10.1176/appi.ajp.2013.13050597

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