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American Journal of Psychiatry

Volume 167, Issue 8

August 2010

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In This Issue

August 2010

Page:A24
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.167.8.a24

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Editorial

August 2010

The Complexity of Complex PTSD

Richard A. Bryant, Ph.D.

Pages:879–881
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10040606

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August 2010

An Opioid Deficit in Borderline Personality Disorder: Self-Cutting, Substance Abuse, and Social Dysfunction

Antonia S. New, M.D., and
Barbara Stanley, Ph.D.

Pages:882–885
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10040634

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August 2010

Abrupt Withdrawal of Antidepressant Treatment

Robert Freedman, M.D.

Pages:886–888
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10050783

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August 2010

S-Adenosyl Methionine (SAMe) Augmentation in Major Depressive Disorder

J. Craig Nelson, M.D.

Pages:889–891
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10040627

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Clinical Case Conference

August 2010

Bipolar Disorder and Pregnancy: Maintaining Psychiatric Stability in the Real World of Obstetric and Psychiatric Complications

Vivien K. Burt, M.D., Ph.D.,
Caryn Bernstein, M.D.,
Wendy S. Rosenstein, M.D., and
Lori L. Altshuler, M.D.

Pages:892–897
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2009.09081248

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Images in Psychiatry

August 2010

Samuel Tuke's Description of the Retreat

Raymond Raad, M.D., M.P.H., and
George Makari, M.D.

Page:898
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10020265

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Reviews and Overviews

August 2010

Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and Disease

Anne S. Bassett, M.D.,
Stephen W. Scherer, Ph.D., and
Linda M. Brzustowicz, M.D.

Pages:899–914
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2009.09071016

Abstract
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ObjectiveStructural variations of DNA, such as copy number variations (CNVs), are recognized to contribute both to normal genomic variability and to risk for human diseases. For example, schizophrenia has an established connection with 22q11.2 deletions. ...

Article

August 2010

Treatment for PTSD Related to Childhood Abuse: A Randomized Controlled Trial

Marylene Cloitre, Ph.D.,
K. Chase Stovall-McClough, Ph.D.,
Kate Nooner, Ph.D.,
Patty Zorbas, B.A.,
Stephanie Cherry, M.S.W.,
Christie L. Jackson, Ph.D.,
Weijin Gan, M.S., and
Eva Petkova, Ph.D.

Pages:915–924
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09081247

Abstract
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ObjectivePosttraumatic stress disorder (PTSD) related to childhood abuse is associated with features of affect regulation and interpersonal disturbances that substantially contribute to impairment. Existing treatments do not address these problems or the ...

August 2010

Dysregulation of Regional Endogenous Opioid Function in Borderline Personality Disorder

Alan R. Prossin, M.D.,
Tiffany M. Love,
Robert A. Koeppe, Ph.D.,
Jon-Kar Zubieta, M.D., Ph.D., and
Kenneth R. Silk, M.D.

Pages:925–933
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09091348

Abstract
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ObjectiveBorderline personality disorder is characterized by a lack of effective regulation of emotional responses. The authors investigated the role of the endogenous opioid system and μ-opioid receptors in emotion regulation in borderline personality ...

August 2010

Illness Risk Following Rapid Versus Gradual Discontinuation of Antidepressants

Ross J. Baldessarini, M.D.,
Leonardo Tondo, M.D., M.S.,
Carmen Ghiani, M.D., and
Beatrice Lepri, Psy.D.

Pages:934–941
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09060880

Abstract
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ObjectiveRapid discontinuation of some psychotropic medications is followed by discontinuation symptoms as well as an increased risk of early illness recurrence. Recurrence occurs earlier after rapid than after gradual discontinuation with lithium and ...

August 2010

S-Adenosyl Methionine (SAMe) Augmentation of Serotonin Reuptake Inhibitors for Antidepressant Nonresponders With Major Depressive Disorder: A Double-Blind, Randomized Clinical Trial

George I. Papakostas, M.D.,
David Mischoulon, M.D., Ph.D.,
Irene Shyu, B.A.,
Jonathan E. Alpert, M.D., Ph.D., and
Maurizio Fava, M.D.

Pages:942–948
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2009.09081198

Abstract
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ObjectiveDespite the progressive increase in the number of antidepressants, many patients with major depressive disorder continue to be symptomatic. Clearly, there is an urgent need to develop better tolerated and more effective treatments for this ...

August 2010

Genome-Wide Association Study of Major Recurrent Depression in the U.K. Population

Cathryn M. Lewis, Ph.D.,
Mandy Y. Ng, Ph.D.,
Amy W. Butler, Ph.D.,
Sarah Cohen-Woods, Ph.D.,
Rudolf Uher, M.D., Ph.D., M.R.C.Psych.,
Katrina Pirlo, B.Sc.,
Michael E. Weale, Ph.D.,
Alexandra Schosser, M.D., Ph.D.,
Ursula M. Paredes, Ph.D.,
Margarita Rivera, Ph.D.,
Nicholas Craddock, F.R.C.Psych., Ph.D.,
Mike J. Owen, F.R.C.Psych., Ph.D.,
Lisa Jones, Ph.D.,
Ian Jones, M.R.C.Psych., Ph.D.,
Ania Korszun, Ph.D., M.D., M.R.C.Psych.,
Katherine J. Aitchison, M.R.C.Psych., Ph.D.,
Jianxin Shi, Ph.D.,
John P. Quinn, Ph.D.,
Alasdair MacKenzie, Ph.D.,
Peter Vollenweider, M.D.,
Gerard Waeber, M.D.,
Simon Heath, Ph.D.,
Mark Lathrop, Ph.D.,
Pierandrea Muglia, M.D.,
Michael R. Barnes, Ph.D.,
John C. Whittaker, Ph.D.,
Federica Tozzi, M.D.,
Florian Holsboer, M.D., Ph.D.,
Martin Preisig, M.D., M.P.H.,
Anne E. Farmer, M.D., F.R.C.Psych.,
Gerome Breen, Ph.D.,
Ian W. Craig, Ph.D., and
Peter McGuffin, F.R.C.P., F.R.C.Psych., Ph.D.

Pages:949–957
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09091380

Abstract
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ObjectiveStudies of major depression in twins and families have shown moderate to high heritability, but extensive molecular studies have failed to identify susceptibility genes convincingly. To detect genetic variants contributing to major depression, ...

August 2010

Efficacy of Meta-Cognitive Therapy for Adult ADHD

Mary V. Solanto, Ph.D.,
David J. Marks, Ph.D.,
Jeanette Wasserstein, Ph.D.,
Katherine Mitchell, Psy.D.,
Howard Abikoff, Ph.D.,
Jose Ma. J. Alvir, Dr.P.H., and
Michele D. Kofman, Ph.D.

Pages:958–968
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2009.09081123

Abstract
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ObjectiveThe authors investigated the efficacy of a 12-week manualized meta-cognitive therapy group intervention designed to enhance time management, organization, and planning in adults with attention deficit hyperactivity disorder (ADHD). MethodEighty-...

August 2010

Telescoping and Gender Differences in Alcohol Dependence: New Evidence From Two National Surveys

Katherine M. Keyes, M.P.H., M.Phil.,
Silvia S. Martins, M.D., Ph.D.,
Carlos Blanco, M.D., Ph.D., and
Deborah S. Hasin, Ph.D.

Pages:969–976
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2009.09081161

Abstract
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ObjectiveThe course of alcohol disorders in women is often described as "telescoped" compared to that in men, with a later age at initiation of alcohol use but shorter times from use to dependence and treatment. This study examined evidence for such a ...

August 2010

Basal Ganglia Surface Morphology and the Effects of Stimulant Medications in Youth With Attention Deficit Hyperactivity Disorder

Loren J. Sobel, M.D., M.S.,
Ravi Bansal, Ph.D.,
Tiago V. Maia, Ph.D.,
Juan Sanchez, M.S.,
Luigi Mazzone, M.D.,
Kathleen Durkin, M.S.,
Jun Liu, Ph.D.,
Xuejun Hao, Ph.D.,
Iliyan Ivanov, M.D.,
Ann Miller, M.D., Ph.D.,
Laurence L. Greenhill, M.D., and
Bradley S. Peterson, M.D.

Pages:977–986
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09091259

Abstract
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ObjectiveDisturbances in the basal ganglia portions of cortico-striato-thalamo-cortical circuits likely contribute to the symptoms of attention deficit hyperactivity disorder (ADHD). The authors examined the morphologic features of the basal ganglia ...

August 2010

Cannabis Use and the Course of Schizophrenia: 10-Year Follow-Up After First Hospitalization

Daniel J. Foti, M.A.,
Roman Kotov, Ph.D.,
Lin T. Guey, Ph.D., and
Evelyn J. Bromet, Ph.D.

Pages:987–993
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09020189

Abstract
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ObjectiveThe authors examined the relationship between cannabis use and the course of illness in schizophrenia over 10 years of follow-up after first psychiatric hospitalization. MethodThe authors assessed 229 patients with a schizophrenia spectrum ...

Letter to the Editor

August 2010

Analysis of Antipsychotic Dose Reduction

Hiroyuki Uchida, M.D., Ph.D.,
Takefumi Suzuki, M.D., Ph.D.,
Hiroyoshi Takeuchi, M.D., and
David C. Mamo, M.D., M.Sc., F.R.C.P.C.

Page:994
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030409

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August 2010

Reply to Uchida et al. Letter

Chuan-Yue Wang, M.D., Ph.D.,
Yu-Tao Xiang, M.D., Ph.D., and
Gabor S. Ungvari, M.D., Ph.D.

Pages:994–995
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030409r

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August 2010

The Value of Data on Suicidality by Treatment Arm

Eric G. Smith, M.D., M.P.H.

Page:995
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10040468

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August 2010

Reply to Smith Letter

Pierre Blier, M.D., Ph.D.

Pages:995–996
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10040468r

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August 2010

Placebo Group Needed for Interpretation of Combination Trial

Rif S. El-Mallakh, M.D.,
Gagandeep Kaur, M.D., and
Steven Lippman, M.D.

Page:996
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030453

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August 2010

Reply to El-Mallakh et al. Letter

Pierre Blier, M.D., Ph.D., and
A. John Rush, M.D.

Pages:996–997
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030453r

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August 2010

The Difficulty of Making a Sole Diagnosis of Antisocial Personality Disorder

Scott A. Freeman, M.D.

Page:997
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030394

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August 2010

Reply to Freeman Letter

Daniel Antonius, Ph.D.

Pages:997–998
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10030394r

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August 2010

Elevated Prevalence of Generalized Anxiety Disorder in Adults With 22q11.2 Deletion Syndrome

Wai Lun Alan Fung, M.D., S.M., F.R.C.P.C.,
Rebecca McEvilly, M.D.,
Jessica Fong, B.Sc.,
Candice Silversides, M.D., M.S., F.R.C.P.C.,
Eva Chow, M.D., M.P.H.,, F.R.C.P.C., and
Anne Bassett, M.D., F.R.C.P.C.

Page:998
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.09101463

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Book Forum

August 2010

The Rise and Fall of the Biopsychosocial Model: Reconciling Art and Science in Psychiatry

Kenneth S. Kendler, M.D.

Pages:999–1000
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10020268

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August 2010

Personal Identity and Fractured Selves: Perspectives From Philosophy, Ethics, and Neuroscience

Victor I. Reus, M.D.

Page:1000
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10020267

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August 2010

Principles and Practice of Child and Adolescent Forensic Mental Health

Roslyn Seligman, M.D.

Pages:1000–1001
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10020272

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August 2010

Depersonalization: A New Look at a Neglected Syndrome

Eric Hollander, M.D.

Page:1001
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.10020273

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Books Received

August 2010

Page:1002
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.167.8.1002

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Official Actions

August 2010

Official Actions

Pages:1003–1008
Published Online:1 August 2010

https://doi.org/10.1176/appi.ajp.2010.167.8.1003

First Page
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