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Late-onset akathisia--an indicant of covert dyskinesia: two case reports

Published Online:https://doi.org/10.1176/ajp.140.5.611

Two patients receiving long-term depot antipsychotic treatment developed late-onset akathisia characterized by emergence toward the end of each injection interval. Drug dose reduction provoked exacerbation of the akathisia and the appearance of choreiform limb dyskinesia. The authors discuss a possible pathophysiological mechanism.

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