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Case report of tricyclic-induced delirium at a therapeutic drug concentration

Published Online:https://doi.org/10.1176/ajp.140.11.1517

A patient receiving a standard dose of imipramine developed a drug- induced delirium. Her plasma antidepressant level was in the low therapeutic range. Thus, tricyclic-induced delirium may in some cases be an idiosyncratic phenomenon unrelated to plasma drug concentration.

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